设计_____烫伤喷雾剂；正交设计；提取工艺

正交设计优选烫伤喷雾剂提取工艺

http://www.100md.com 《时珍国医国药》 2005年第9期

设计,,烫伤喷雾剂；正交设计；提取工艺,1材料与仪器,2方法,3正交实验及方差分析,4结果与讨论,参考文献：

     摘要：目的：为烫伤喷雾剂剂型改革研究优选提取工艺。方法：以小檗碱、总生物碱、干浸膏得率为指标，采用正交实验优选烫伤喷雾剂提取工艺条件。结果：确定其工艺条件为：A3 B3 C3 D2，即溶剂为8倍量95%乙醇，浸提时间为40 min/次，提取次数为3次。结论：该工艺提取的有效成分含量高。

    关键词：烫伤喷雾剂；正交设计；提取工艺

    Study on Extraction Technology of Scald Sprays by Orthogonal Design

    MA Xiaoli1，2, YAO Zihua1, HAO Lijing2

    (1.College of Chemistry and Environmental Science,Hebei University，Key Lab of The Analytical Science and Technology of Hebei Province, Baoding, 071002, China; 2.Hebei Medical College for Continuing Education,Baoding, 071000, China)

    Abstract:Objective:To optimize the extraction process of Scald Sprays.Methods:The orthogonal design was used to select the optimum extraction of Scald Sprays according to the amounts of berberine,alkaloid and extract.Results:The optimum extracting condition was A3B3C3D2,that was,to reflux the herb for 3 times and duration of extraction was 40 min for each time with 8 times amount of 95%alcohol.Conclusion:The optimized process is stable and highly efficient.

    Key words:Scald Sprays;Orthogonal Design;Extraction technology

    烫伤喷雾剂是一临床经验方 ......

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